What is LATE?
Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a recently characterized type of dementia. Similar to other forms of brain disorders, such as Alzheimer’s disease, LATE causes problems with memory and thinking but has different underlying causes. Researchers identified LATE based on results of autopsy studies that revealed abnormal clusters of a protein called TDP-43. TDP-43 is …