Many but not all people with Down syndrome develop Alzheimer’s disease when they get older. People with Down syndrome are born with an extra copy of chromosome 21, which carries a gene that produces a specific protein called amyloid precursor protein (APP). Too much APP protein leads to a buildup of protein clumps called beta-amyloid plaques in the brain. […]
Alzheimer’s Disease in People With Down Syndrome Read More »
Alzheimer’s disease disproportionately affects individuals with Down syndrome. In fact, estimates suggest that 50% or more of people with Down syndrome will develop Alzheimer’s disease as they age. Adults with Down syndrome typically begin to show symptoms of Alzheimer’s disease in their 50s or 60s. Scientists are working hard to understand why people with Down
Alzheimer’s disease and Down Syndrome Read More »
Many, but not all, people with Down syndrome develop Alzheimer’s disease when they get older. Scientists are conducting basic studies, biomarker studies, and clinical trials to better understand why some people with Down syndrome develop dementia while others do not, measure cognitive and biological changes, and develop treatments. Learn more about research opportunities for people
The Alzheimer’s-Down Syndrome Connection Read More »
A message from the National Institute on Aging… Many, but not all, people with Down syndrome develop Alzheimer’s disease when they get older. Scientists are conducting basic studies, biomarker studies, and clinical trials to better understand why some people with Down syndrome develop dementia while others do not, measure cognitive and biological changes, and develop
What’s the connection between Alzheimer’s and Down Syndrome? Read More »
Many, but not all, people with Down syndrome develop Alzheimer’s disease when they get older. Scientists are conducting basic studies, biomarker studies, and clinical trials to better understand why some people with Down syndrome develop dementia while others do not, measure cognitive and biological changes, and develop treatments. The NIH fact sheet Alzheimer’s Disease in
Alzheimer’s Disease and Down Syndrome Read More »
