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Alzheimer’s Disease and Down Syndrome

Many, but not all, people with Down syndrome develop Alzheimer’s disease when they get older. Scientists are conducting basic studies, biomarker studies, and clinical trials to better understand why some people with Down syndrome develop dementia while others do not, measure cognitive and biological changes, and develop treatments.

The NIH fact sheet Alzheimer’s Disease in People with Down Syndrome explores:

  • The connection between Down syndrome and Alzheimer’s
  • Alzheimer’s symptoms
  • Current Down syndrome and Alzheimer’s research
  • Ways to participate in research

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Last Updated on April 28, 2020

Published by Raj C. Shah, MD

I am geriatrician and an Associate Professor in the Department of Family Medicine and the Rush Alzheimer's Disease Center.

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