Limbic-predominant age-related TDP-43 encephalopathy (LATE) is a recently characterized type of dementia. Similar to other forms of brain disorders, such as Alzheimer’s disease, LATE causes problems with memory and thinking but has different underlying causes.
Researchers identified LATE based on results of autopsy studies that revealed abnormal clusters of a protein called TDP-43. TDP-43 is involved in other brain disorders, including amyotrophic lateral sclerosis and frontotemporal lobar degeneration. In LATE, it exhibits a different pattern of brain changes and tends to affect people over the age of 80.
Learn more about limbic-predominant age-related TDP-43 encephalopathy (LATE).
